Inova 8/2

Generic Name: benzoyl peroxide and salicylic acid topical (BEN zoe il per OX ide and sal i SIL ik A sid)

Brand Names: Cleanse & Treat, Inova 4/1, Inova 8/2

What is Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oil and dirt to be washed away.

Salicylic acid is a peeling agent that causes shedding of the outer layer of skin.

The combination of benzoyl peroxide and salicylic acid is used to treat severe acne.

Benzoyl peroxide and salicylic acid may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

Do not use this medication if you are allergic to benzoyl peroxide (Benzagel, Clear by Design, Fostex, Oxy-10, Panoxyl, and others) or to salicylic acid (aspirin, Compound W, Duofilm, Stri-Dex, and others).

This medication is not for use in treating mild forms of acne. The strength of benzoyl peroxide contained in this medication is higher than that used in many over-the-counter acne products. Severe skin irritation can result from improper use of this product.

Do not share this medication with anyone, even if they have the same symptoms you do. Do not use this medication on anyone under 18 years old without the advice of a doctor.

What should I discuss with my health care provider before using Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

Do not use this medication if you are allergic to benzoyl peroxide (Benzagel, Clear by Design, Fostex, Oxy-10, Panoxyl, and others) or to salicylic acid (aspirin, Compound W, Duofilm, Stri-Dex, and others).

Before using benzoyl peroxide and salicylic acid, tell your doctor if you are allergic to any drugs.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether benzoyl peroxide and salicylic acid passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

This medication is not for use in treating mild forms of acne. The strength of benzoyl peroxide contained in this medication is higher than that used in many over-the-counter acne products. Severe skin irritation can result from improper use of this product.

Do not share this medication with anyone, even if they have the same symptoms you do. Do not use this medication on anyone under 18 years old without the advice of a doctor.

How should I use Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Apply the medicated pad to clean, dry skin. Use only mild skin cleansers or those your doctor has prescribed.

This medication can bleach or discolor fabric, hair, or other surfaces it comes in contact with. Use with care to avoid damaging colored surfaces.

If this medication causes skin irritation, apply a cool compress to your skin (such as a washcloth wet with cold water) and call your doctor.

Store this medication at room temperature away from moisture and heat.

Keep each medicated pad in its foil pouch until you are ready to use it.

What happens if I miss a dose?

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a benzoyl peroxide and salicylic acid overdose may include scaly or peeling skin, redness, or swelling.

What should I avoid while using Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Benzoyl peroxide and salicylic acid can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.

Avoid getting this medication in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use benzoyl peroxide topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Inova 8/2 (benzoyl peroxide and salicylic acid topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have severe skin irritation.

Less serious side effects may include dry skin or mild irritation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Inova 8/2 (benzoyl peroxide and salicylic acid topical)?

There may be other drugs that can interact with benzoyl peroxide and salicylic acid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Inova 8/2 resources

• Inova 8/2 Side Effects (in more detail)
• Inova 8/2 Use in Pregnancy & Breastfeeding
• Inova 8/2 Drug Interactions
• 0 Reviews for Inova 8/2 - Add your own review/rating

Compare Inova 8/2 with other medications

• Acne

Where can I get more information?

• Your pharmacist can provide more information about benzoyl peroxide and salicylic acid.

See also: Inova 8/2 side effects (in more detail)

Gilenya

Pronunciation: fin-GOL-i-mod
Generic Name: Fingolimod
Brand Name: Gilenya

Gilenya is used for:

Reducing the number of relapses and delaying disability in certain patients with multiple sclerosis (MS).

Gilenya is a sphingosine 1-phosphate receptor modulator. Exactly how it works is not known, but it is thought to work by decreasing the number of certain white blood cells (lymphocytes) that enter the central nervous system (CNS).

Do NOT use Gilenya if:

• you are allergic to any ingredient in Gilenya


• you have an active infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Gilenya:

Some medical conditions may interact with Gilenya. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a slow heart rate (less than 55 beats per minute), high blood pressure, or heart problems (eg, irregular heartbeat, heart block, sick sinus syndrome, prolonged QT interval, heart failure)


• if you have a history of long-term infection or an infection that keeps coming back, fainting, eye problems (eg, an inflammation called uveitis, macular edema), lung or breathing problems, liver or kidney problems, or diabetes


• if you have a weakened immune system, a fever, or you have not had chickenpox or the chickenpox vaccination


• if you have had a vaccine within 1 month before you start Gilenya

Some MEDICINES MAY INTERACT with Gilenya. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiarrhythmics (eg, amiodarone, procainamide, quinidine, sotalol), beta-blockers (eg, atenolol), or calcium channel blockers (eg, diltiazem) because the risk of slow or irregular heartbeat may be increased


• Medicine for cancer, medicine that may weaken your immune system, or other medicines for MS (eg, mitoxantrone, natalizumab) because the risk of infection may be increased


• Ketoconazole because it may increase the risk of Gilenya's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Gilenya may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Gilenya:

Use Gilenya as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Gilenya comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Gilenya refilled.


• Take Gilenya by mouth with or without food.


• Your first dose of Gilenya will be given in a doctor's office, hospital, or clinic. You will be observed for 6 hours following your first dose.


• Take Gilenya on a regular schedule to get the most benefit from it. Taking Gilenya at the same time each day will help you remember to take it.


• Continue to take Gilenya even if you feel well. Do not miss any doses.


• If you miss a dose of Gilenya, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss taking Gilenya for more than 2 weeks, contact your doctor before you start to take it again.

Ask your health care provider any questions you may have about how to use Gilenya.

Important safety information:

• Slow heartbeat may occur after you start Gilenya, especially after your first dose. Your health care provider will watch you for symptoms of slow heartbeat for 6 hours after your first dose. If you experience slow heartbeat, your heart rate will usually return to normal within 1 month after you start Gilenya. Tell your doctor right away if you experience dizziness, slow or irregular heartbeat, or unusual tiredness.


• Do NOT take more than the recommended dose without checking with your doctor.


• Gilenya may lower the ability of your body to fight infection while you take it and for up to 2 months after you stop taking it. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.


• If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.


• Do not receive a live vaccine (eg, measles, mumps) while you are taking Gilenya and for up to 2 months after you stop taking it. Talk with your doctor before you receive any vaccine.


• Cases of a certain type of blood cancer (lymphoma) have occurred in patients taking Gilenya. It is not known if these cases were related to Gilenya. Contact your doctor with any questions or concerns.


• Women who may become pregnant should use an effective form of birth control while they take Gilenya and for 2 months after they stop taking Gilenya. If you have questions about effective birth control, talk with your doctor.


• Gilenya may interfere with certain lab tests, including peripheral blood lymphocyte counts. Be sure your doctor and lab personnel know you are taking Gilenya.


• Lab tests, including electrocardiogram (ECG), complete blood cell counts, blood pressure, lung function, liver function, and eye exams, may be performed while you use Gilenya. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Gilenya should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Gilenya may cause harm to the fetus. Do not become pregnant while you are using it or for 2 months after you stop using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Gilenya while you are pregnant. It is not known if Gilenya is found in breast milk. Do not breast-feed while taking Gilenya.

Possible side effects of Gilenya:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; cough; diarrhea; headache; mild hair loss; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; dizziness; eye pain; new or worsening breathing problems (eg, shortness of breath); one-sided weakness; severe or persistent headache; slow or irregular heartbeat; slurred speech; symptoms of infection (eg, fever, chills, sore throat, severe or persistent cough, body aches, nausea or vomiting, increased or painful urination); symptoms of liver problems (eg, dark urine; loss of appetite; pale stools; severe or persistent nausea, vomiting, or stomach pain; yellowing of the skin or eyes); unexpected weight loss; unusual tiredness or weakness; vision changes (eg, blurred vision, decreased clearness of vision, blind spot, sensitivity to light, unusually colored or tinted vision).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Gilenya side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest tightness or discomfort.

Proper storage of Gilenya:

Store Gilenya at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in the original blister pack away from heat, moisture, and light. Do not store in the bathroom. Keep Gilenya out of the reach of children and away from pets.

General information:

• If you have any questions about Gilenya, please talk with your doctor, pharmacist, or other health care provider.


• Gilenya is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Gilenya. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Gilenya resources

• Gilenya Side Effects (in more detail)
• Gilenya Use in Pregnancy & Breastfeeding
• Gilenya Drug Interactions
• Gilenya Support Group
• 14 Reviews for Gilenya - Add your own review/rating

• Gilenya Prescribing Information (FDA)


• Gilenya Monograph (AHFS DI)


• Gilenya Advanced Consumer (Micromedex) - Includes Dosage Information


• Gilenya Consumer Overview

Compare Gilenya with other medications

• Multiple Sclerosis

Otic anti-infectives

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Otic anti-infectives are generally available as ear drops and contain anti-infective agents that either have antibacterial or antifungal activity. These agents either kill or inhibit bacterial or fungal growth. They are used to treat bacterial or fungal infections of the ear.

See also

Medical conditions associated with otic anti-infectives:

• Acute Otitis Externa
• Bacterial Infection
• Otitis Externa
• Otitis Media

Drug List:

Zinotic-Drops

Acetasol-Otic

Borofair-Solution

Cetraxal

Chlorpram-Z-Drops

Cresylate-Drops

Domeboro-Otic

Floxin-Otic

Star-Otic

Vosol

Zinotic-Es-Drops

Vitafol-OB+DHA

Generic Name: prenatal multivitamins (PRE nay tal VYE ta mins)

Brand Names: Advance Care Plus, Bright Beginnings, Cavan Folate, Cavan One, Cavan-Heme OB, Cenogen Ultra, CitraNatal Rx, Co Natal FA, Complete Natal DHA, Complete-RF, CompleteNate, Concept OB, Docosavit, Dualvit OB, Duet, Edge OB, Elite OB 400, Femecal OB, Folbecal, Folcaps Care One, Folivan-OB, Foltabs, Gesticare, Icar Prenatal, Icare Prenatal Rx, Inatal Advance, Infanate DHA, Kolnatal DHA, Lactocal-F, Marnatal-F, Maternity, Maxinate, Mission Prenatal, Multi-Nate 30, Multinatal Plus, Nata 29 Prenatal, Natachew, Natafort, Natelle, Neevo, Nestabs, Nexa Select with DHA, Novanatal, NovaStart, O-Cal Prenatal, OB Complete, OB Natal One, Ob-20, Obtrex DHA, OptiNate, Paire OB Plus DHA, PNV Select, PNV-Total, PR Natal 400, Pre-H-Cal, Precare, PreferaOB, Premesis Rx, PrenaCare, PrenaFirst, PrenaPlus, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal Elite, Prenatal Multivitamins, Prenatal Plus, Prenatal S, Prenatal-U, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenavite FC, PreNexa, PreQue 10, Previte Rx, PrimaCare, Pruet DHA, RE OB Plus DHA, Renate, RightStep, Rovin-NV, Se-Care, Se-Natal One, Se-Plete DHA, Se-Tan DHA, Select-OB, Seton ET, Strongstart, Stuart Prenatal with Beta Carotene, Tandem OB, Taron-BC, Tri Rx, TriAdvance, TriCare, Trimesis Rx, Trinate, Triveen-PRx RNF, UltimateCare Advance, Ultra-Natal, Vemavite PRX 2, VeNatal FA, Verotin-BY, Verotin-GR, Vinacal OR, Vinatal Forte, Vinate Advanced (New Formula), Vinate AZ, Vinate Care, Vinate Good Start, Vinate II (New Formula), Vinate III, Vinate One, Vitafol-OB, VitaNatal OB plus DHA, Vitaphil, Vitaphil Aide, Vitaphil Plus DHA, Vitaspire, Viva DHA, Vol-Nate, Vol-Plus, Vol-Tab Rx, Vynatal F.A., Zatean-CH, Zatean-PN

What are Vitafol-OB+DHA (prenatal multivitamins)?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.

Prenatal vitamins are a combination of many different vitamins that are normally found in foods and other natural sources.

Prenatal vitamins are used to provide the additional vitamins needed during pregnancy. Minerals may also be contained in prenatal multivitamins.

Prenatal vitamins may also be used for purposes not listed in this medication guide.

What is the most important information I should know about prenatal vitamins?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.

Never take more than the recommended dose of a multivitamin. Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin.

What should I discuss with my healthcare provider before taking prenatal vitamins?

Many vitamins can cause serious or life-threatening side effects if taken in large doses. Do not take more of this medication than directed on the label or prescribed by your doctor.

Before taking prenatal vitamins, tell your doctor about all of your medical conditions.

You may need to continue taking prenatal vitamins if you breast-feed your baby. Ask your doctor about taking this medication while breast-feeding.

How should I take prenatal vitamins?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Never take more than the recommended dose of prenatal vitamins.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.

Take your prenatal vitamin with a full glass of water.

Swallow the regular tablet or capsule whole. Do not break, chew, crush, or open it.

The chewable tablet must be chewed or allowed to dissolve in your mouth before swallowing. You may also allow the chewable tablet to dissolve in drinking water, fruit juice, or infant formula (but not milk or other dairy products). Drink this mixture right away.

Use prenatal vitamins regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat. Keep prenatal vitamins in their original container. Storing vitamins in a glass container can ruin the medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.

What should I avoid while taking prenatal vitamins?

Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Avoid the regular use of salt substitutes in your diet if your multivitamin contains potassium. If you are on a low-salt diet, ask your doctor before taking a vitamin or mineral supplement.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the prenatal vitamin.

Prenatal vitamins side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

When taken as directed, prenatal vitamins are not expected to cause serious side effects. Less serious side effects may include:

• 
  

  upset stomach;

  
  


• 
  

  headache; or

  
  


• 
  

  unusual or unpleasant taste in your mouth.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect prenatal vitamins?

Vitamin and mineral supplements can interact with certain medications, or affect how medications work in your body. Before taking a prenatal vitamin, tell your doctor if you also use:

• 
  

  diuretics (water pills);

  
  


• 
  

  heart or blood pressure medications;

  
  


• 
  

  tretinoin (Vesanoid);

  
  


• 
  

  isotretinoin (Accutane, Amnesteen, Clavaris, Sotret);

  
  


• 
  

  trimethoprim and sulfamethoxazole (Cotrim, Bactrim, Gantanol, Gantrisin, Septra, TMP/SMX); or

  
  


• 
  

  an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.

  
  

This list is not complete and other drugs may interact with prenatal vitamins. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Vitafol-OB+DHA resources

• Vitafol-OB+DHA Side Effects (in more detail)
• Vitafol-OB+DHA Use in Pregnancy & Breastfeeding
• Vitafol-OB+DHA Drug Interactions
• Vitafol-OB+DHA Support Group
• 0 Reviews for Vitafol-OB+DHA - Add your own review/rating

• Cal-Nate MedFacts Consumer Leaflet (Wolters Kluwer)


• CareNatal DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• CitraNatal 90 DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• CitraNatal Assure Prescribing Information (FDA)


• CitraNatal Harmony Prescribing Information (FDA)


• Concept DHA Prescribing Information (FDA)


• Docosavit Prescribing Information (FDA)


• Duet DHA with Ferrazone MedFacts Consumer Leaflet (Wolters Kluwer)


• Folbecal MedFacts Consumer Leaflet (Wolters Kluwer)


• Folcal DHA Prescribing Information (FDA)


• Folcaps Care One Prescribing Information (FDA)


• Gesticare DHA Prescribing Information (FDA)


• Gesticare DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• Inatal Advance Prescribing Information (FDA)


• Inatal Ultra Prescribing Information (FDA)


• Multi-Nate DHA Prescribing Information (FDA)


• Multi-Nate DHA Extra Prescribing Information (FDA)


• MultiNatal Plus MedFacts Consumer Leaflet (Wolters Kluwer)


• Natelle One Prescribing Information (FDA)


• Neevo Caplets MedFacts Consumer Leaflet (Wolters Kluwer)


• Neevo DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• OB Complete 400 MedFacts Consumer Leaflet (Wolters Kluwer)


• Paire OB Plus DHA Prescribing Information (FDA)


• PreNexa MedFacts Consumer Leaflet (Wolters Kluwer)


• PreNexa Prescribing Information (FDA)


• PreferaOB Prescribing Information (FDA)


• Prenatal Plus Prescribing Information (FDA)


• Prenatal Plus Iron Prescribing Information (FDA)


• Prenate Elite Prescribing Information (FDA)


• Prenate Elite MedFacts Consumer Leaflet (Wolters Kluwer)


• Prenate Elite tablets


• Prenate Essential Prescribing Information (FDA)


• PrimaCare Advantage MedFacts Consumer Leaflet (Wolters Kluwer)


• PrimaCare ONE capsules


• PrimaCare One MedFacts Consumer Leaflet (Wolters Kluwer)


• Renate DHA Prescribing Information (FDA)


• Se-Natal 19 Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Se-Natal 19 Prescribing Information (FDA)


• Tandem DHA Prescribing Information (FDA)


• Tandem OB Prescribing Information (FDA)


• TriAdvance Prescribing Information (FDA)


• Triveen-One MedFacts Consumer Leaflet (Wolters Kluwer)


• Triveen-PRx RNF Prescribing Information (FDA)


• UltimateCare ONE NF Prescribing Information (FDA)


• Ultra NatalCare MedFacts Consumer Leaflet (Wolters Kluwer)


• Vinate AZ Prescribing Information (FDA)


• Vitafol-One MedFacts Consumer Leaflet (Wolters Kluwer)


• Zatean-CH Prescribing Information (FDA)

Compare Vitafol-OB+DHA with other medications

• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Where can I get more information?

• Your pharmacist can provide more information about prenatal vitamins.

See also: Vitafol-OB+DHA side effects (in more detail)

Barbiturate anticonvulsants

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Barbiturate anticonvulsants are a group of drugs derived from barbituric acid and they act by suppressing activity of the central nervous system. Barbiturate anticonvulsants enhance the action of GABA, which is an inhibitory neurotransmitter, and inhibits initiation of discharge that would start the seizure. Barbiturates facilitate GABA-mediated opening of chloride channels and increases effectiveness of GABA.

Barbiturates are used to treat all types of seizures except absence seizures.

See also

Medical conditions associated with barbiturate anticonvulsants:

• Benign Essential Tremor
• Epilepsy
• Hyperbilirubinemia
• Insomnia
• Sedation
• Seizures

Drug List:

Mebaral

Mysoline

Luminal

Solfoton

Pegvisomant

Pronunciation: peg-VI-soe-mant
Generic Name: Pegvisomant
Brand Name: Somavert

Pegvisomant is used for:

Treating acromegaly in patients who have not responded to surgery, radiation therapy, or other medical procedures, or who are not candidates for those treatments.

Pegvisomant is a growth hormone receptor antagonist. It works by blocking the site of action for growth hormone, which helps to block the effects of growth hormone.

Do NOT use Pegvisomant if:

• you are allergic to any ingredient in Pegvisomant, including polyethylene glycol


• you are allergic to latex

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pegvisomant:

Some medical conditions may interact with Pegvisomant. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have diabetes, a tumor or other growths, liver problems, or a history of alcohol abuse

Some MEDICINES MAY INTERACT with Pegvisomant. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Narcotic pain medicine (eg, codeine) because it may decrease Pegvisomant's effectiveness


• Insulin or oral hypoglycemic agents because the risk of their side effects may be increased by Pegvisomant

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pegvisomant may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pegvisomant:

Use Pegvisomant as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Pegvisomant. Talk to your pharmacist if you have questions about this information.


• Pegvisomant is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Pegvisomant at home, a health care provider will teach you how to use it. Be sure you understand how to use Pegvisomant. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Do not use Pegvisomant if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.


• Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle.


• Pegvisomant must be mixed before you use it. Follow your doctor's instructions on how to mix Pegvisomant.


• Do not shake Pegvisomant after mixing it. Hold the vial between the palms of both hands and gently roll it to dissolve the powder.


• Use Pegvisomant within 6 hours after mixing it. Throw away any unused medicine left in the vial after your dose. If you do not use Pegvisomant within 6 hours after you mix it, throw it away.


• Choose a different injection site each day (eg, upper arm, upper thigh, stomach area, buttocks) to help prevent lumps at the injection sites.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.


• If you miss a dose of Pegvisomant skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Pegvisomant.

Important safety information:

• Pegvisomant may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Pegvisomant with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Diabetes patients - Pegvisomant may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Pegvisomant may interfere with certain lab tests, including some growth hormone level tests. Be sure your doctor and lab personnel know you are taking Pegvisomant.


• Lab tests, including growth hormone blood levels, insulin-like growth factor blood levels, and liver function, may be performed while you use Pegvisomant. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Pegvisomant should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pegvisomant while you are pregnant. It is not known if Pegvisomant is found in breast milk. If you are or will be breast-feeding while you use Pegvisomant, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Pegvisomant:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; flu-like symptoms (eg, mild fever or chills, muscle aches, weakness); nausea; pain, redness, or itching at the injection site; sinus inflammation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; swelling of the legs and feet; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, unusual tiredness, severe or persistent nausea or stomach pain, loss of appetite); thickening of the skin or lumps at the injection site; unusual weight gain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Pegvisomant side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased fatigue.

Proper storage of Pegvisomant:

Before mixing, store Pegvisomant in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. After mixing, Pegvisomant may be kept at room temperature for up to 6 hours. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pegvisomant out of the reach of children and away from pets.

General information:

• If you have any questions about Pegvisomant, please talk with your doctor, pharmacist, or other health care provider.


• Pegvisomant is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Pegvisomant. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Pegvisomant resources

• Pegvisomant Side Effects (in more detail)
• Pegvisomant Use in Pregnancy & Breastfeeding
• Pegvisomant Drug Interactions
• Pegvisomant Support Group
• 1 Review for Pegvisomant - Add your own review/rating

• Pegvisomant Professional Patient Advice (Wolters Kluwer)


• Pegvisomant Monograph (AHFS DI)


• pegvisomant Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information


• Somavert Prescribing Information (FDA)


• Somavert Consumer Overview

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Amylin analogs

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Amylin analogs are used in the treatment of diabetes. They are stable synthetic compounds, which are administered subcutaneously before meals, and work similarly to the physiological amylin.

Amylin is a 37 amino acid polypeptide hormone that is secreted with insulin from the beta cells in the pancreas. In diabetes, as less insulin is secreted there is also a deficiency of amylin. Amylin assists insulin in postprandial glucose control. It inhibits glucagon secretion, delays gastric emptying and signals satiety, suppressing the intake of food.

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Medical conditions associated with amylin analogs:

• Diabetes, Type 1
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